Temple University cherry "T" logo

School or College Name

Search Keywords

Ananias A Escalante

Temple University Logo

Ananias A Escalante

  • College of Science and Technology

    • Biology

      • Professor

Biography

I have built an international research program in ecology and evolution of infectious diseases with emphasis on Malaria. My program focuses on establishing bridges among anthropological, epidemiological, and evolutionary biology perspectives by interpreting genetic patterns from pathogens. I have experience managing complex research and training projects that demand strong international collaborations.

Courses Taught

Number

Name

Level

BIOL 3112

Fundamentals of Genomic Evolutionary Medicine

Undergraduate

BIOL 3128

Genomics and Infectious Disease Dynamics

Undergraduate

BIOL 5112

Fundamentals of Genomic Evolutionary Medicine

Graduate

BIOL 5128

Genomics and Infectious Disease Dynamics

Graduate

Selected Publications

Recent

  • Ramey, A., Buchheit, R., Uher-Koch, B., Reed, J., Pacheco, M., Escalante, A., & Schmutz, J. (2021). Negligible evidence for detrimental effects of Leucocytozoon infections among Emperor Geese (Anser canagicus) breeding on the Yukon-Kuskokwim Delta, Alaska. International Journal for Parasitology: Parasites and Wildlife, 16, 103-112. doi: 10.1016/j.ijppaw.2021.08.006.

  • Uwimana, A., Umulisa, N., Venkatesan, M., Svigel, S., Zhou, Z., Munyaneza, T., Habimana, R., Rucogoza, A., Moriarty, L., Sandford, R., Piercefield, E., Goldman, I., Ezema, B., Talundzic, E., Pacheco, M., Escalante, A., Ngamije, D., Mangala, J., Kabera, M., Munguti, K., Murindahabi, M., Brieger, W., Musanabaganwa, C., Mutesa, L., Udhayakumar, V., Mbituyumuremyi, A., Halsey, E., & Lucchi, N. (2021). Association of Plasmodium falciparum kelch13 R561H genotypes with delayed parasite clearance in Rwanda: an open-label, single-arm, multicentre, therapeutic efficacy study. The Lancet Infectious Diseases, 21(8), 1120-1128. doi: 10.1016/S1473-3099(21)00142-0.

  • Pond, S.K., Wisotsky, S., Escalante, A., Magalis, B., & Weaver, S. (2021). Contrast-FEL - A Test for Differences in Selective Pressures at Individual Sites among Clades and Sets of Branches. Molecular Biology and Evolution, 38(3), 1184-1198. doi: 10.1093/molbev/msaa263.

  • Córdoba, O.H., Ferreira, F., Pacheco, M., Escalante, A., & Braga, Ã. (2021). Plasmodium scorzai, n. sp., a new case of non-erythrocytic species within lizard malaria parasites. Parasitology. doi: 10.1017/S0031182021000895.

  • Raballah, E., Anyona, S., Cheng, Q., Munde, E., Hurwitz, I., Onyango, C., Ndege, C., Hengartner, N., Pacheco, M., Escalante, A., Lambert, C., Ouma, C., Obama, H., Scheider, K., Seidenberg, P., McMahon, B., & Perkins, D. (2021). Complement component 3 mutations alter the longitudinal risk of pediatric malaria and severe malarial anemia. Experimental Biology and Medicine. doi: 10.1177/15353702211056272.

  • Pacheco, M., Parish, C., Hauck, T., Aguilar, R., & Escalante, A. (2020). The endangered California Condor (Gymnogyps californianus) population is exposed to local haemosporidian parasites. Scientific Reports, 10(1). doi: 10.1038/s41598-020-74894-0.

  • Pacheco, M., Schneider, K., Cheng, Q., Munde, E., Ndege, C., Onyango, C., Raballah, E., Anyona, S., Ouma, C., Perkins, D., & Escalante, A. (2020). Changes in the frequencies of Plasmodium falciparum dhps and dhfr drug-resistant mutations in children from Western Kenya from 2005 to 2018: the rise of Pfdhps S436H. Malaria Journal, 19(1). doi: 10.1186/s12936-020-03454-8.

  • Pacheco, M., Ceríaco, L., Matta, N., Vargas-Ramírez, M., Bauer, A., & Escalante, A. (2020). A phylogenetic study of Haemocystidium parasites and other Haemosporida using complete mitochondrial genome sequences. Infection, Genetics and Evolution, 85. doi: 10.1016/j.meegid.2020.104576.

  • Louzada, J., Almeida, N.d., Araujo, J.d., Silva, J., Carvalho, T., Escalante, A., & Oliveira-Ferreira, J. (2020). The impact of imported Malaria by gold miners in roraima: Characterizing the spatial dynamics of autochthonous and imported malaria in an urban region of boa vista. Memorias Do Instituto Oswaldo Cruz, 115(6), 1-10. doi: 10.1590/0074-02760200043.

  • Pacheco, M., Forero-Penã, D., Schneider, K., Chavero, M., Gamardo, A., Figuera, L., Kadakia, E., Grillet, M., Oliveira-Ferreira, J., & Escalante, A. (2020). Malaria in Venezuela: Changes in the complexity of infection reflects the increment in transmission intensity. Malaria Journal, 19(1). doi: 10.1186/s12936-020-03247-z.

  • González, L., Pacheco, M., Escalante, A., Maldonado, A.J., Cepeda, A., Rodríguez-Fandiño, O., Vargas‐Ramírez, M., & Matta, N. (2019). Haemocystidium spp., a species complex infecting ancient aquatic turtles of the family Podocnemididae: First report of these parasites in Podocnemis vogli from the Orinoquia. International Journal for Parasitology: Parasites and Wildlife, 10, 299-309. doi: 10.1016/j.ijppaw.2019.10.003.

  • Wiese, D., Escalante, A., Murphy, H., Henry, K., & Gutierrez-Velez, V. (2019). Integrating environmental and neighborhood factors in MaxEnt modeling to predict species distributions: A case study of Aedes albopictus in southeastern Pennsylvania. PLoS ONE, 14(10). doi: 10.1371/journal.pone.0223821.

  • Lotta, I., ValkiÅ«nas, G., Pacheco, M., Escalante, A., Hernández, S., & Matta, N. (2019). Disentangling Leucocytozoon parasite diversity in the neotropics: Descriptions of two new species and shortcomings of molecular diagnostics for leucocytozoids. International Journal for Parasitology: Parasites and Wildlife, 9, 159-173. doi: 10.1016/j.ijppaw.2019.05.002.

  • Pacheco, M., Kadakia, E., Chaudhary, Z., Perkins, D., Kelley, J., Ravishankar, S., Cranfield, M., Talundzic, E., Udhayakumar, V., & Escalante, A. (2019). Evolution and genetic diversity of the k13 gene associated with artemisinin delayed parasite clearance in plasmodium falciparum. Antimicrobial Agents and Chemotherapy, 63(8). doi: 10.1128/AAC.02550-18.

  • Escalante, A. & Pacheco, M. (2019). Malaria molecular epidemiology: An evolutionary genetics perspective. Microbiology Spectrum, 7(4). doi: 10.1128/microbiolspec.AME-0010-2019.

  • Manrique, P., Miranda-Alban, J., Alarcon-Baldeon, J., Ramirez, R., Carrasco-Escobar, G., Herrera, H., Guzman-Guzman, M., Rosas-Aguirre, A., Llanos-Cuentas, A., Vinetz, J., Escalante, A., & Gamboa, D. (2019). Microsatellite analysis reveals connectivity among geographically distant transmission zones of Plasmodium vivax in the Peruvian Amazon: A critical barrier to regional malaria elimination. PLoS Neglected Tropical Diseases, 13(11). doi: 10.1371/journal.pntd.0007876.

  • Pacheco, A., García-Amado, M.A., Manzano, J., Matta, N., & Escalante, A. (2019). Blood parasites infecting the Hoatzin (Opisthocomus hoazin), a unique neotropical folivorous bird. PeerJ, 2019(2). doi: 10.7717/peerj.6361.

  • Ferreira-Junior, F., Dutra, D.D.A., Silveira, P., Pacheco, R., Witter, R., Ramos, D.D.S., Pacheco, M., Escalante, A., & Braga, Ã. (2018). A new pathogen spillover from domestic to wild animals: Plasmodium juxtanucleare infects free-living passerines in Brazil. Parasitology, 145(14), 1949-1958. doi: 10.1017/S003118201800077X.

  • Chaudhry, S., Lwin, N., Phelan, D., Escalante, A., & Battistuzzi, F. (2018). Comparative analysis of low complexity regions in Plasmodia. Scientific Reports, 8(1). doi: 10.1038/s41598-017-18695-y.

  • Rodrigues, P., Valdivia, H., Oliveira, T.D., Alves, J., Duarte, A., Cerutti-Junior, C., Buery, J., Brito, C., Souza, J.D., Hirano, Z., Bueno, M., Catão-Dias, J., Malafronte, R., Ladeia-Andrade, S., Mita, T., Santamaria, A., Calzada, J., Tantular, I., Kawamoto, F., Raijmakers, L., Mueller, I., Pacheco, M., Escalante, A., Felger, I., & Ferreira, M. (2018). Human migration and the spread of malaria parasites to the New World. Scientific Reports, 8(1). doi: 10.1038/s41598-018-19554-0.

  • Pacheco, M., Cepeda, A., Bernotienė, R., Lotta, I., Matta, N., ValkiÅ«nas, G., & Escalante, A. (2018). Primers targeting mitochondrial genes of avian haemosporidians: PCR detection and differential DNA amplification of parasites belonging to different genera. International Journal for Parasitology, 48(8), 657-670. doi: 10.1016/j.ijpara.2018.02.003.

  • Matta, N., González, L., Pacheco, M., Escalante, A., Moreno, A., González, A., & Calderón-Espinosa, M. (2018). Plasmodium parasites in reptiles from the Colombia Orinoco-Amazon basin: a re-description of Plasmodium kentropyxi Lainson R, Landau I, Paperna I, 2001 and Plasmodium carmelinoi Lainson R, Franco CM, da Matta R, 2010. Parasitology Research, 117(5), 1357-1370. doi: 10.1007/s00436-018-5815-9.

  • Pacheco, M., Schneider, K., Céspedes, N., Herrera, S., Arévalo-Herrera, M., & Escalante, A. (2018). Limited differentiation among Plasmodium vivax populations from the northwest and to the south Pacific Coast of Colombia: A malaria corridor? PLoS Neglected Tropical Diseases, 13(3). doi: 10.1371/journal.pntd.0007310.

  • Pacheco, M., Matta, N., Valkiünas, G., Parker, P., Mello, B., Stanley, C., Lentino, M., Garcia-Amado, M., Cranfield, M., Pond, S., & Escalante, A. (2018). Mode and rate of evolution of haemosporidian mitochondrial genomes: Timing the radiation of avian parasites. Molecular Biology and Evolution, 35(2), 383-403. doi: 10.1093/molbev/msx285.

  • Schneider, K. & Escalante, A. (2018). Erratum: Correction: A Likelihood Approach to Estimate the Number of Co-Infections (PloS one (2014) 9 7 (e97899)). PloS One, 13(2), e0192877. doi: 10.1371/journal.pone.0192877.

  • Valverde, P.M., Cardenas, O.N., Ramirez, R., Carrasco-Escobar, G., Contreras-Mancilla, J., Rodriguez, H., Speybroeck, N., Rosas-Aguirre, A., Rosas-Aguirre, A., Llanos-Cuentas, A., Llanos-Cuentas, A., Escalante, A., Vilela, D.G., Vilela, D.G., Vilela, D.G., & Vilela, D.G. (2022). HUMAN MOBILITY RELATED TRANSMISSION OF NEW PARASITE GENETIC CLUSTERS IN MAZAN BASIN IN THE PERUVIAN AMAZON. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 99(4), 110-110. Retrieved from http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000461386602354&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=abcd71df5a6dac31fd219478b0a9c638.

  • Pacheco, M.A., Chaurio, R.A., Cornejo, O.E., Durrego, E., Stanley, C.E., Castillo, A.I., Herrera, S., & Escalante, A.A. EVOLUTION OF THE TRANSMISSION-BLOCKING VACCINE CANDIDATES PVS28 AND PVS25 IN PLASMODIUM VIVAX: GEOGRAPHIC DIFFERENTIATION AND EVIDENCE OF POSITIVE SELECTION. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 95(5), 296-297. Retrieved from http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000412851502467&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=abcd71df5a6dac31fd219478b0a9c638.

  • Rodrigues, P.T., Valdivia, H.O., Oliveira, T.C., Barbosa, S., Duarte, A.M.R., Junior, C.C., Buery, J.C., Brito, C.F., Mueller, I., Escalante, A.A., Pacheco, M.A., Malafronte, R.S., Alves, J.M., Felger, I., & Ferreira, M.U. ORIGIN AND SPREAD OF PLASMODIUM VIVAX AND P. FALCIPARUM IN THE AMERICAS. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 95(5), 296-296. Retrieved from http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000412851502466&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=abcd71df5a6dac31fd219478b0a9c638.

  • Erkenswick, G., Watsa, M., Pacheco, M., Escalante, A., & Parker, P. (2017). Chronic plasmodium brasilianum infections in wild peruvian tamarins. PLoS ONE, 12(9). doi: 10.1371/journal.pone.0184504.

  • Gómez, K.M., Caicedo, M., Gaitán, A., Herrera-Varela, M., Arce, M., Vallejo, A., Padilla, J., Chaparro, P., Pacheco, M., Escalante, A., Arevalo-Herrera, M., & Herrera, S. (2017). Characterizing the malaria rural-to-urban transmission interface: The importance of reactive case detection. PLoS Neglected Tropical Diseases, 11(7). doi: 10.1371/journal.pntd.0005780.

  • Castillo, A., Pacheco, M.A., & Escalante, A. (2017). Evolution of the merozoite surface protein 7 (msp7) family in Plasmodium vivax and P. falciparum: A comparative approach. Infection, Genetics and Evolution, 50, 7-19. doi: 10.1016/j.meegid.2017.01.024.

  • Glenn, E.M., Achieng, A.O., Cheng, Q., Kempaiah, P., Escalante, A., & Perkins, D.J. (2022). PLASMODIUM FALCIPARUM ERYTHROCYTE MEMBRANE PROTEIN 1 (PFEMP1) VARIANT EXPRESSION PROFILES IN KENYAN CHILDREN WITH SEVERE MALARIAL ANEMIA FROM WESTERN KENYA. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 97(5), 478-478. Retrieved from http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000423215204256&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=abcd71df5a6dac31fd219478b0a9c638.