David A Liberles

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David A Liberles

  • College of Science and Technology

    • Biology

      • Professor

Courses Taught

Number

Name

Level

BIOL 2296

Genetics

Undergraduate

BIOL 3403

Genomic Biology

Undergraduate

BIOL 4391

Accelerated Research in Biology

Undergraduate

BIOL 5403

Genomics

Graduate

BIOL 5509

Computational Genomics

Graduate

BIOL 8210

Seminar

Graduate

Selected Publications

Recent

  • Ritchie, A., Stark, T., & Liberles, D. (2021). Inferring the number and position of changes in selective regime in a non-equilibrium mutation-selection framework. BMC Ecology and Evolution, 21(1). doi: 10.1186/s12862-021-01770-4.

  • Harman, J., Cuff, A., Settele, J., Jacobus, L., Liberles, D., & Traulsen, A. (2021). Inaugural BMC Ecology and Evolution image competition: the winning images. BMC Ecology and Evolution, 21(1). doi: 10.1186/s12862-021-01886-7.

  • Harman, J., Cuff, A., Settele, J., Jacobus, L., Liberles, D., & Traulsen, A. (2021). Correction to: Inaugural BMC Ecology and Evolution image competition: the winning images (BMC Ecology and Evolution, (2021), 21, 1, (157), 10.1186/s12862-021-01886-7). BMC Ecology and Evolution, 21(1). doi: 10.1186/s12862-021-01891-w.

  • Stark, T., Kaufman, R., Maltepes, M., Chi, P., & Liberles, D. (2021). Detecting Selection on Segregating Gene Duplicates in a Population. Journal of Molecular Evolution, 89(8), 554-564. doi: 10.1007/s00239-021-10024-2.

  • Stark, T.L. & Liberles, D.A. (2021). Characterizing Amino Acid Substitution with Complete Linkage of Sites on a Lineage. Genome Biology and Evolution, 13(10), evab225. doi: 10.1093/gbe/evab225.

  • Selberg, A., Gaucher, E., & Liberles, D. (2021). Ancestral Sequence Reconstruction: From Chemical Paleogenetics to Maximum Likelihood Algorithms and Beyond. Journal of Molecular Evolution, 89(3), 157-164. doi: 10.1007/s00239-021-09993-1.

  • Goldman, A. & Liberles, D. (2021). The Journal of Molecular Evolution Turns 50. Journal of Molecular Evolution, 89(3), 119-121. doi: 10.1007/s00239-021-10000-w.

  • Liberles, D. (2021). 2020 Zuckerkandl Prize. Journal of Molecular Evolution, 89(1-2), 1. doi: 10.1007/s00239-020-09990-w.

  • Chi, P., Kosater, W., & Liberles, D. (2020). Detecting signatures of positive selection against a backdrop of compensatory processes. Molecular Biology and Evolution, 37(11), 3353-3362. doi: 10.1093/molbev/msaa161.

  • Wilson, A., Kosater, W., & Liberles, D. (2020). Evolutionary Processes and Biophysical Mechanisms: Revisiting Why Evolved Proteins Are Marginally Stable. Journal of Molecular Evolution, 88(5), 415-417. doi: 10.1007/s00239-020-09948-y.

  • Diao, J., Stark, T., Liberles, D., O’Reilly, M., & Holland, B. (2020). Level-dependent QBD models for the evolution of a family of gene duplicates. Stochastic Models, 36(2), 285-311. doi: 10.1080/15326349.2019.1680296.

  • Liberles, D., Chang, B., Geiler-Samerotte, K., Goldman, A., Hey, J., Kaçar, B., Meyer, M., Murphy, W., Posada, D., & Storfer, A. (2020). Emerging Frontiers in the Study of Molecular Evolution. Journal of Molecular Evolution, 88(3), 211-226. doi: 10.1007/s00239-020-09932-6.

  • Liberles, D. (2020). 2019 Zuckerkandl Prize. Journal of Molecular Evolution, 88(2), 121. doi: 10.1007/s00239-019-09924-1.

  • Northover, D., Shank, S., & Liberles, D. (2020). Characterizing lineage-specific evolution and the processes driving genomic diversification in chordates. BMC Evolutionary Biology, 20(1). doi: 10.1186/s12862-020-1585-y.

  • Liberles, D. (2019). A New Editorial Beginning at Journal of Molecular Evolution. Journal of Molecular Evolution, 87(2-3), 69-71. doi: 10.1007/s00239-019-09888-2.

  • Yohe, L., Liu, L., Dávalos, L., & Liberles, D. (2019). Protocols for the Molecular Evolutionary Analysis of Membrane Protein Gene Duplicates. In Methods in Molecular Biology, 1851 (pp. 49-62). doi: 10.1007/978-1-4939-8736-8_3.

  • Fragata, I., Blanckaert, A., Louro, M.D., Liberles, D., & Bank, C. (2019). Evolution in the light of fitness landscape theory. Trends in Ecology and Evolution, 34(1), 69-82. doi: 10.1016/j.tree.2018.10.009.

  • Liberles, D. & Teufel, A. (2018). Evolution and structure of proteins and proteomes. Genes, 9(12). doi: 10.3390/genes9120583.

  • Teufel, A., Ritchie, A., Wilke, C., & Liberles, D. (2018). Using the mutation-selection framework to characterize selection on protein sequences. Genes, 9(8). doi: 10.3390/genes9080409.

  • Platt, A., Weber, C., & Liberles, D. (2018). Protein evolution depends on multiple distinct population size parameters. BMC Evolutionary Biology, 18(1). doi: 10.1186/s12862-017-1085-x.

  • Chi, P., Kim, D., Lai, J., Bykova, N., Weber, C., Kubelka, J., & Liberles, D. (2018). A new parameter-rich structure-aware mechanistic model for amino acid substitution during evolution. Proteins: Structure, Function and Bioinformatics, 86(2), 218-228. doi: 10.1002/prot.25429.

  • Liberles, D. & Holland, B. (2018). Evolutionary models. In Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, 1-3 (pp. 712-718). doi: 10.1016/B978-0-12-809633-8.20256-2.

  • Arenas, M., Weber, C., Liberles, D., & Bastolla, U. (2017). ProtASR: An Evolutionary Framework for Ancestral Protein Reconstruction with Selection on Folding Stability. Systematic Biology, 66(6), 1054-1064. doi: 10.1093/sysbio/syw121.

  • Hermansen, R., Oswald, B., Knight, S., Shank, S., Northover, D., Korunes, K., Michel, S., & Liberles, D. (2017). The Adaptive Evolution Database (TAED): A New Release of a Database of Phylogenetically Indexed Gene Families from Chordates. Journal of Molecular Evolution, 85(1-2), 46-56. doi: 10.1007/s00239-017-9806-8.

  • Orlenko, A., Chi, P., & Liberles, D. (2017). Characterizing the roles of changing population size and selection on the evolution of flux control in metabolic pathways. BMC Evolutionary Biology, 17(1). doi: 10.1186/s12862-017-0962-7.

  • Stark, T., Liberles, D., Holland, B., & O’Reilly, M. (2017). Analysis of a mechanistic Markov model for gene duplicates evolving under subfunctionalization. BMC Evolutionary Biology, 17(1), 1-16. doi: 10.1186/s12862-016-0848-0.