Courses Taught
Number | Name | Level |
|---|---|---|
SCTC 1001 | CST First Year Seminar | Undergraduate |
CHEM 5102 | Data Analysis and Evidence | Graduate |
CHEM 8007 | Biotransformation of Drugs and Xenobiotics | Graduate |
CHEM 8310 | Special Topics in Analytical Chemistry: Biotransformation of Drugs and Xenobiotics | Graduate |
Selected Publications
Recent
Gogineni, V., Nael, M., Chaurasiya, N., Elokely, K., McCurdy, C., Rimoldi, J., Cutler, S., Tekwani, B., & León, F. (2021). Computationally assisted lead optimization of novel potent and selective mao-b inhibitors. Biomedicines, 9(10). doi: 10.3390/biomedicines9101304.
Manandhar, A., Srinivasulu, V., Hamad, M., Tarazi, H., Omar, H., Colussi, D., Gordon, J., Childers, W., Klein, M., Al-Tel, T., Abou-Gharbia, M., & Elokely, K. (2021). Discovery of Novel Small-Molecule Inhibitors of SARS-CoV-2 Main Protease as Potential Leads for COVID-19 Treatment. Journal of Chemical Information and Modeling, 61(9), 4745-4757. doi: 10.1021/acs.jcim.1c00684.
El-Awady, R., Saleh, E., Hamoudi, R., Ramadan, W., Mazitschek, R., Nael, M., Elokely, K., Abou-Gharbia, M., Childers, W., Srinivasulu, V., Aloum, L., Menon, V., & Al-Tel, T. (2021). Discovery of novel class of histone deacetylase inhibitors as potential anticancer agents. Bioorganic and Medicinal Chemistry, 42. doi: 10.1016/j.bmc.2021.116251.
Jahan, M., Leon, F., Fronczek, F., Elokely, K., Rimoldi, J., Khan, S., & Avery, M. (2021). Structure–activity relationships of the antimalarial agent artemisinin 10. Synthesis and antimalarial activity of enantiomers of rac-5β-hydroxy-d-secoartemisinin and analogs: Implications regarding the mechanism of action. Molecules, 26(14). doi: 10.3390/molecules26144163.
Manandhar, A., Blass, B., Colussi, D., Almi, I., Abou-Gharbia, M., Klein, M., & Elokely, K. (2021). Targeting SARS-CoV-2 M3CLpro by HCV NS3/4a Inhibitors: In Silico Modeling and in Vitro Screening. Journal of Chemical Information and Modeling, 61(2), 1020-1032. doi: 10.1021/acs.jcim.0c01457.
Larit, F., Elokely, K., Nael, M., Benyahia, S., León, F., Cutler, S., & Ghoneim, M. (2021). Proposed mechanism for the antitrypanosomal activity of Quercetin and Myricetin isolated from hypericum Afrum lam: Phytochemistry, in vitro testing and modeling studies. Molecules, 26(4). doi: 10.3390/molecules26041009.
Elsebaie, H., Elhamamsy, M., Elokely, K., & Eldawy, M. (2021). Investigation and analytical applications of the reaction of n1-methylni-cotinamide and active methylene containing drugs. Current Pharmaceutical Analysis, 17(10), 1331-1338. doi: 10.2174/1573412917999200922131030.
Ragab, E., Shaheen, U., Bader, A., Elokely, K., & Ghoneim, M. (2021). Computational study and biological evaluation of isolated saponins from the fruits of gleditsia aquatica and gleditsia caspica. Records of Natural Products, 15(2), 142-147. doi: 10.25135/rnp.202.20.08.1764.
Emam, A., Abdellatif, K., Amin, N., & Elokely, K. (2021). HCV NS5B RdRp mutations and their effects on ligand binding affinity. International Journal of Modelling and Simulation. doi: 10.1080/02286203.2021.1923953.
Aboelmagd, M., Elokely, K., Said, A., Haggag, E., Ghoneim, M., & Ross, S. (2021). New selective human mao-b inhibitors from the stems of erythrina corallodendron l. Records of Natural Products, 15(5), 368-379. doi: 10.25135/rnp.229.21.01.1940.
Al-Ashmawy, A., Elokely, K., Perez-Leal, O., Rico, M., Gordon, J., Mateo, G., Omar, A., Abou-Gharbia, M., & Childers, W. (2020). Discovery and SAR of Novel Disubstituted Quinazolines as Dual PI3Kalpha/mTOR Inhibitors Targeting Breast Cancer. ACS Medicinal Chemistry Letters, 11(11), 2156-2164. doi: 10.1021/acsmedchemlett.0c00289.
Childers, W., Elokely, K., & Abou-Gharbia, M. (2020). The Resurrection of Phenotypic Drug Discovery. ACS Medicinal Chemistry Letters, 11(10), 1820-1828. doi: 10.1021/acsmedchemlett.0c00006.
Al-Madboly, L., Ali, S., Fakharany, E., Ragab, A., Khedr, E., & Elokely, K. (2020). Stress-Based Production, and Characterization of Glutathione Peroxidase and Glutathione S-Transferase Enzymes From Lactobacillus plantarum. Frontiers in Bioengineering and Biotechnology, 8. doi: 10.3389/fbioe.2020.00078.
Kiick, K., Klein, M., Elokely, K., Gianti, E., & Carnevale, V. (2019). Designing biomacromolecular materials with tailored (poly)peptide conjugates. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 258. Retrieved from http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000525061505040&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=abcd71df5a6dac31fd219478b0a9c638.
Eldin, S.S., Radwan, M., Wanas, A., Habib, A., Kassem, F., Hammoda, H., Khan, S., Klein, M., Elokely, K., & Elsohly, M. (2018). Bioactivity-Guided Isolation of Potential Antidiabetic and Antihyperlipidemic Compounds from Trigonella stellata. Journal of Natural Products, 81(5), 1154-1161. doi: 10.1021/acs.jnatprod.7b00707.
Aboelmagd, M., Elokely, K., Zaki, M., Said, A., Haggag, E., & Ross, S. (2018). Anti-inflammatory of pyrrolizidine alkaloids from Heliotropium digynum. Medicinal Chemistry Research, 27(4), 1066-1073. doi: 10.1007/s00044-017-2128-y.
Ghoneim, M., Musa, A., El-Hela, A., & Elokely, K. (2018). Evaluation and understanding the molecular basis of the antimethicillin-resistant Staphylococcus aureus activity of secondary metabolites isolated from Lamium amplexicaule. Pharmacognosy Magazine, 14(55), S3-S7. doi: 10.4103/pm.pm_541_17.
Larit, F., Elokely, K., Chaurasiya, N., Benyahia, S., Nael, M., León, F., Abu-Darwish, M., Efferth, T., Wang, Y., Belouahem-Abed, D., Benayache, S., Tekwani, B., & Cutler, S. (2018). Inhibition of human monoamine oxidase A and B by flavonoids isolated from two Algerian medicinal plants. Phytomedicine, 40, 27-36. doi: 10.1016/j.phymed.2017.12.032.
Ibrahim, A., Elokely, K., Ferreira, D., & Ragab, A. (2018). Microbial Oxidation of the Fusidic Acid Side Chain by Cunninghamella echinulata. Molecules, 23(4). doi: 10.3390/molecules23040970.
Osman, A.G., Elokely, K., Yadav, V., Carvalho, P., Radwan, M., Slade, D., Gul, W., Khan, S., Dale, O., Husni, A., Klein, M., Cutler, S., Ross, S., & ElSohly, M. (2018). Bioactive products from singlet oxygen photooxygenation of cannabinoids. European Journal of Medicinal Chemistry, 143, 983-996. doi: 10.1016/j.ejmech.2017.11.043.
Yadav, V., Elokely, K., & Klein, M. (2017). Comparative analysis of the structural determinants of endogenous cannabinoids and activity of illicit drugs on cannabinoid receptors. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 253. Retrieved from http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000430568507483&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=abcd71df5a6dac31fd219478b0a9c638.
Al-Ashmawy, A., Ragab, F., Elokely, K., Anwar, M., Perez-Leal, O., Rico, M., Gordon, J., Bichenkov, E., Mateo, G., Kassem, E., Hegazy, G., Abou-Gharbia, M., & Childers, W. (2017). Design, synthesis and SAR of new-di-substituted pyridopyrimidines as ATP-competitive dual PI3Kα/mTOR inhibitors. Bioorganic and Medicinal Chemistry Letters, 27(14), 3117-3122. doi: 10.1016/j.bmcl.2017.05.044.
Bryant, K., Chae, Y., Martinez, R., Gordon, J., Elokely, K., Kossenkov, A., Grant, S., Childers, W., Abou-Gharbia, M., & Altieri, D. (2017). A Mitochondrial-targeted purine-based HSP90 antagonist for leukemia therapy. Oncotarget, 8(68), 112184-112198. doi: 10.18632/oncotarget.23097.