Biography
Swati Nagar obtained her Ph.D. in Pharmaceutics at the University of Minnesota in 2003. She completed a postdoctoral fellowship in Pharmacology at Fox Chase Cancer Center in 2005. Swati joined Temple University School of Pharmacy, Department of Pharmaceutical Sciences in 2005 as Assistant Professor, and was promoted to the rank of Associate Professor in 2011. She teaches Pharm D and graduate pharmacokinetics. Swati’s research focuses on enzyme kinetics and in collaboration with Dr. Ken Korzekwa she is developing methods to better understand complex kinetics of time-dependent inhibition. Another key collaborative area of research with the Korzekwa lab is developing models to predict intracellular concentrations in the presence of drug transporters. Additionally, her lab has a long-standing interest in understanding the disposition of conjugated metabolites, specifically the pharmacokinetics of metabolites with respect to their formation and transport. Swati is the current Chair of the Delaware Valley Drug Metabolism Discussion Group, current Chair of the AAPS PPDM Drug Metabolism Focus Group, a member of the steering committee of the International Transporter Consortium, and a member of several professional organizations such as AAAS, ASPET, AAPS and ISSX. She is currently serving on the editorial board of Drug Metabolism and Disposition.
Courses Taught
Number | Name | Level |
|---|---|---|
PS 8000 | Topics in Pharmaceutical Sciences | Graduate |
PS 8008 | Advanced Principles of Pharmacokinetics | Graduate |
PS 8125 | Journ Club/Pharmacodynam | Graduate |
PS 8126 | Laboratory Experience in Pharmaceutical Sciences | Graduate |
PS 8127 | Pharmacokinetics | Graduate |
Selected Publications
Recent
Yadav, J., Paragas, E., Korzekwa, K., & Nagar, S. (2020). Time-dependent enzyme inactivation: Numerical analyses of in vitro data and prediction of drug-drug interactions. Pharmacology and Therapeutics, 206. doi: 10.1016/j.pharmthera.2019.107449.
Korzekwa, K. & Nagar, S. (2017). Drug Distribution Part 2. Predicting Volume of Distribution from Plasma Protein Binding and Membrane Partitioning. Pharmaceutical Research, 34(3), 544-551. doi: 10.1007/s11095-016-2086-y.