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Kamel Khalili

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Kamel Khalili

  • Lewis Katz School of Medicine

    • Neuroscience

      • Laura H. Carnell Professor

    • Center for Neurovirology and Gene Editing

      • Chair

Selected Publications

Recent

  • Duggan, M., Ahooyi, T.M., Parikh, V., & Khalili, K. (2021). Neuromodulation of BAG co-chaperones by HIV-1 viral proteins and H2O2: implications for HIV-associated neurological disorders. Cell Death Discovery, 7(1). doi: 10.1038/s41420-021-00424-0.

  • Torkzaban, B., Ahooyi, T.M., Duggan, M., Amini, S., & Khalili, K. (2020). Cross-talk between lipid homeostasis and endoplasmic reticulum stress in neurodegeneration: Insights for HIV-1 associated neurocognitive disorders (HAND). Neurochemistry International, 141. doi: 10.1016/j.neuint.2020.104880.

  • Torkzaban, B., Natarajaseenivasan, K., Ahooyi, T.M., Shekarabi, M., Amini, S., Langford, T., & Khalili, K. (2020). The lncRNA LOC102549805 (U1) modulates neurotoxicity of HIV-1 Tat protein. Cell Death and Disease, 11(10). doi: 10.1038/s41419-020-03033-4.

  • Dash, P., Kaminski, R., Bella, R., Su, H., Mathews, S., Ahooyi, T., Chen, C., Mancuso, P., Sariyer, R., Ferrante, P., Donadoni, M., Robinson, J., Sillman, B., Lin, Z., Hilaire, J., Banoub, M., Elango, M., Gautam, N., Mosley, R., Poluektova, L., McMillan, J., Bade, A., Gorantla, S., Sariyer, I., Burdo, T., Young, W., Amini, S., Gordon, J., Jacobson, J., Edagwa, B., Khalili, K., & Gendelman, H. (2019). Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice. Nature Communications, 10(1). doi: 10.1038/s41467-019-10366-y.

  • Ahooyi, T.M., Torkzaban, B., Shekarabi, M., Tahrir, F., Decoppet, E., Cotto, B., Langford, D., Amini, S., & Khalili, K. (2019). Perturbation of synapsins homeostasis through HIV-1 Tat-mediated suppression of BAG3 in primary neuronal cells. Cell Death and Disease, 10(7). doi: 10.1038/s41419-019-1702-2.

  • Sariyer, I., Gordon, J., Burdo, T., Wollebo, H., Gianti, E., Donadoni, M., Bellizzi, A., Cicalese, S., Loomis, R., Robinson, J., Carnevale, V., Steiner, J., Ozdener, M., Miller, A., Amini, S., Klein, M., & Khalili, K. (2019). Suppression of Zika Virus Infection in the Brain by the Antiretroviral Drug Rilpivirine. Molecular Therapy. doi: 10.1016/j.ymthe.2019.10.006.

  • Ahooyi, T.M., Shekarabi, M., Torkzaban, B., Langford, T., Burdo, T., Gordon, J., Datta, P., Amini, S., & Khalili, K. (2018). Dysregulation of Neuronal Cholesterol Homeostasis upon Exposure to HIV-1 Tat and Cocaine Revealed by RNA-Sequencing. Scientific Reports, 8(1). doi: 10.1038/s41598-018-34539-9.

  • Bella, R., Kaminski, R., Mancuso, P., Young, W., Chen, C., Sariyer, R., Fischer, T., Amini, S., Ferrante, P., Jacobson, J., Kashanchi, F., & Khalili, K. (2018). Removal of HIV DNA by CRISPR from Patient Blood Engrafts in Humanized Mice. Molecular Therapy - Nucleic Acids, 12, 275-282. doi: 10.1016/j.omtn.2018.05.021.