Biography
Dr. Mohammad F. Kiani is Professor of the Department of Mechanical Engineering. Dr. Kiani’s expertise is in biofluid mechanics, targeted drug delivery, and radiation oncology. Dr. Kiani co-founded Engineering World Health with Dr. Robert Malkin, served as its president for several years, and currently serves on its board of directors.
Labs: Biofluidics Laboratory
Research Interests
- Microfluidic Systems
- Targeted Drug Delivery
- Leukocyte Biology
Courses Taught
Number | Name | Level |
|---|---|---|
ENGR 3001 | Engineering Economics | Undergraduate |
Selected Publications
Recent
Yang, Q., Wijerathne, H., Langston, J., Kiani, M., & Kilpatrick, L. (2021). Emerging approaches to understanding microvascular endothelial heterogeneity: A roadmap for developing anti-inflammatory therapeutics. International Journal of Molecular Sciences, 22(15). doi: 10.3390/ijms22157770.
Wijerathne, H., Langston, J., Yang, Q., Sun, S., Miyamoto, C., Kilpatrick, L., & Kiani, M. (2021). Mechanisms of radiation-induced endothelium damage: Emerging models and technologies. Radiotherapy and Oncology, 158, 21-32. doi: 10.1016/j.radonc.2021.02.007.
Kilpatrick, L. & Kiani, M. (2020). Experimental approaches to evaluate leukocyte-endothelial cell interactions in sepsis and inflammation. Shock, 53(5), 585-595. doi: 10.1097/SHK.0000000000001407.
Soroush, F., Tang, Y., Mustafa, O., Sun, S., Yang, Q., Kilpatrick, L., & Kiani, M. (2020). Neutrophil-endothelial interactions of murine cells is not a good predictor of their interactions in human cells. FASEB Journal, 34(2), 2691-2702. doi: 10.1096/fj.201900048R.
Silvani, G., Scognamiglio, C., Caprini, D., Marino, L., Chinappi, M., Sinibaldi, G., Peruzzi, G., Kiani, M., & Casciola, C. (2019). Reversible Cavitation-Induced Junctional Opening in an Artificial Endothelial Layer. Small, 15(51). doi: 10.1002/smll.201905375.
Soroush, F., Tang, Y., Guglielmo, K., Engelmann, A., Liverani, E., Patel, A., Langston, J., Sun, S., Kunapuli, S., Kiani, M., & Kilpatrick, L. (2019). Protein Kinase C-Delta (PKCδ) Tyrosine Phosphorylation is a Critical Regulator of Neutrophil-Endothelial Cell Interaction in Inflammation. Shock (Augusta, Ga., 51(5), 538-547. doi: 10.1097/SHK.0000000000001247.
Yang, Q., Langston, J., Tang, Y., Kiani, M., & Kilpatrick, L. (2019). The role of tyrosine phosphorylation of protein kinase C delta in infection and inflammation. International Journal of Molecular Sciences, 20(6). doi: 10.3390/ijms20061498.
Soroush, F., Tang, Y., Zaidi, H., Sheffield, J., Kilpatrick, L., & Kiani, M. (2018). PKCd inhibition as a novel medical countermeasure for radiation-induced vascular damage. FASEB Journal, 32(12), 6436-6444. doi: 10.1096/fj.201701099.
Tang, Y., Soroush, F., Sun, S., Liverani, E., Langston, J., Yang, Q., Kilpatrick, L., & Kiani, M. (2018). Protein kinase C-delta inhibition protects blood-brain barrier from sepsis-induced vascular damage. Journal of Neuroinflammation, 15(1). doi: 10.1186/s12974-018-1342-y.
Yang, F., Soroush, F., Deng, G., Yu, S., Chu, P., Kiani, M., & Ling, H. (2018). Multiple neutrophils tracking in vitro array using high-order temporal information. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, 2018-July, 814-817. doi: 10.1109/EMBC.2018.8512342.
Soroush, F., Tang, Y., Sun, S., Langston, J., Kilpatrick, L.E., & Kiani, M.F. NEUTROPHIL-ENDOTHELIAL INTERACTIONS IN MICE DO NOT ALWAYS PREDICT THEIR INTERACTIONS IN HUMANS. SHOCK, 49(6), 55-56. Retrieved from http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000441343800108&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=abcd71df5a6dac31fd219478b0a9c638.
Tang, Y., Soroush, F., Liverani, E., Sun, S., Langston, J.C., Kilpatrick, L.E., & Kiani, M.F. PROTEIN KINASE C-DELTA INHIBITION PROTECTS THE BRAIN FROM SEPSIS-INDUCED VASCULAR DAMAGE. SHOCK, 49(6), 28-28. Retrieved from http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000441343800044&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=abcd71df5a6dac31fd219478b0a9c638.
Tang, Y., Soroush, F., Sheffield, J., Wang, B., Prabhakarpandian, B., & Kiani, M. (2017). A Biomimetic Microfluidic Tumor Microenvironment Platform Mimicking the EPR Effect for Rapid Screening of Drug Delivery Systems. Scientific Reports, 7(1). doi: 10.1038/s41598-017-09815-9.
Zheng, X., Soroush, F., Long, J., Hall, E., Adishesha, P., Bhattacharya, S., Kiani, M., & Bhalla, V. (2017). Murine glomerular transcriptome links endothelial cell-specific molecule-1 deficiency with susceptibility to diabetic nephropathy. PLoS ONE, 12(9). doi: 10.1371/journal.pone.0185250.
Tehrani, R., Helferty, J., Kiani, M., Suh, W., & Bellas, E. (2017). A project based approach to introduction to engineering. 2017 FYEE Conference.
Luca, R.D., Silvani, G., Scognamiglio, C., Sinibaldi, G., Peruzzi, G., Chinappi, M., Kiani, M., & Casciola, C. (2017). Towards cavitation-enhanced permeability in blood vessel on a chip. AIP Conference Proceedings, 1873. doi: 10.1063/1.4997139.
Kiani, M.F., Soroush, F., Tang, Y., Prabhakarpandian, B., & Kilpatrick, L.E. MODELING PKC-DELTA REGULATION OF NEUTROPHIL-ENDOTHELIAL INTERACTIONS WITH A NOVEL MICROFLUIDICS DEVICE. SHOCK, 47(6), 29-29. Retrieved from http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000401276500051&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=abcd71df5a6dac31fd219478b0a9c638.
Kiani, M.F., Tang, Y., Soroush, F., Prabhakarpandian, B., & Kilpatrick, L.E. MICROVASCULAR NETWORK ON A CHIP. SHOCK, 47(6), 25-25. Retrieved from http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000401276500043&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=abcd71df5a6dac31fd219478b0a9c638.
Cheheltani, R., Pichamuthu, J., Rao, J., Weinbaum, J., Kiani, M., Vorp, D., & Pleshko, N. (2017). Fourier Transform Infrared Spectroscopic Imaging-Derived Collagen Content and Maturity Correlates with Stress in the Aortic Wall of Abdominal Aortic Aneurysm Patients. Cardiovascular Engineering and Technology, 8(1), 70-80. doi: 10.1007/s13239-016-0289-3.
Tang, Y., Soroush, F., Tong, Z., Kiani, M., & Wang, B. (2017). Targeted multidrug delivery system to overcome chemoresistance in breast cancer. International Journal of Nanomedicine, 12, 671-681. doi: 10.2147/IJN.S124770.