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Weidong Yang

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Weidong Yang

  • College of Science and Technology

    • Biology

      • Professor

Courses Taught

Number

Name

Level

BIOL 3096

Cell Structure and Function

Undergraduate

BIOL 3301

Advanced Cell Biology

Undergraduate

BIOL 5301

Cell Biology

Graduate

Selected Publications

Recent

  • Li, Y., Aksenova, V., Tingey, M., Yu, J., Ma, P., Arnaoutov, A., Chen, S., Dasso, M., & Yang, W. (2021). Distinct roles of nuclear basket proteins in directing the passage of mRNA through the nuclear pore. Proceedings of the National Academy of Sciences of the United States of America, 118(37). doi: 10.1073/pnas.2015621118.

  • Tingey, M., Li, Y., & Yang, W. (2021). Protocol for single-molecule fluorescence recovery after photobleaching microscopy to analyze the dynamics and spatial locations of nuclear transmembrane proteins in live cells. STAR Protocols, 2(2). doi: 10.1016/j.xpro.2021.100490.

  • Junod, S., Saredy, J., & Yang, W. (2021). Nuclear import of adeno-associated viruses imaged by high-speed single-molecule microscopy. Viruses, 13(2). doi: 10.3390/v13020167.

  • Li, Y., Tingey, M., Ruba, A., & Yang, W. (2021). High-speed super-resolution imaging of rotationally symmetric structures using SPEED microscopy and 2D-to-3D transformation. Nature Protocols, 16(1), 532-560. doi: 10.1038/s41596-020-00440-x.

  • Mudumbi, K., Czapiewski, R., Ruba, A., Junod, S., Li, Y., Luo, W., Ngo, C., Ospina, V., Schirmer, E., & Yang, W. (2020). Nucleoplasmic signals promote directed transmembrane protein import simultaneously via multiple channels of nuclear pores. Nature Communications, 11(1). doi: 10.1038/s41467-020-16033-x.

  • Junod, S., Kelich, J., Ma, J., & Yang, W. (2020). Nucleocytoplasmic transport of intrinsically disordered proteins studied by high-speed super-resolution microscopy. Protein Science, 29(6), 1459-1472. doi: 10.1002/pro.3845.

  • Tingey, M., Mudumbi, K., Schirmer, E., & Yang, W. (2019). Casting a wider net: Differentiating between inner nuclear envelope and outer nuclear envelope transmembrane proteins. International Journal of Molecular Sciences, 20(21). doi: 10.3390/ijms20215248.

  • Liu, X., Yao, L., Yang, W., Fei, Y., Mi, L., & Ma, J. (2019). Spectroscopic fluorescent tracking of a single molecule in a live cell with a dual-objective fluorescent reflection microscope. Applied Physics Express, 12(11). doi: 10.7567/1882-0786/ab4b16.

  • Ruba, A., Luo, W., Kelich, J., Tingey, M., & Yang, W. (2019). 3D Tracking-Free Approach for Obtaining 3D Super-Resolution Information in Rotationally Symmetric Biostructures. Journal of Physical Chemistry B, 123(24), 5107-5120. doi: 10.1021/acs.jpcb.9b02979.

  • Ruba, A., Luo, W., Kelich, J., & Yang, W. (2019). Microscopy-Independent Approach for Obtaining 3D Super Resolution Information in Rotationally Symmetric Bio-Structures. BIOPHYSICAL JOURNAL, 116(3), 284A-284A. 10.1016/j.bpj.2018.11.1534

  • Li, Y., Aksenova, V., Yu, J., Ma, P., Arnaoutov, A., Dasso, M., & Yang, W. (2019). Copy Number and Function of Individual Disordered Proteins in the Nuclear Pore Complex Revealed by Combining Auxin-Inducible Degron Strategy and High-Speed Single -Molecule Microscopy. BIOPHYSICAL JOURNAL, 116(3), 441A-441A. 10.1016/j.bpj.2018.11.2377

  • Li, Y., Junod, S., Ruba, A., Kelich, J., & Yang, W. (2019). Nuclear export of mRNA molecules studied by SPEED microscopy. Methods, 153, 46-62. doi: 10.1016/j.ymeth.2018.08.005.

  • Ruba, A., Kelich, J., Ma, J., & Yang, W. (2018). Reply to ‘Deconstructing transport-distribution reconstruction in the nuclear-pore complex’. Nature Structural and Molecular Biology, 25(12), 1062-1064. doi: 10.1038/s41594-018-0162-1.

  • Li, Y., Luo, W., & Yang, W. (2018). Nuclear Transport and Accumulation of Smad Proteins Studied by Single-Molecule Microscopy. Biophysical Journal, 114(9), 2243-2251. doi: 10.1016/j.bpj.2018.03.018.

  • Ruba, A., Luo, W., & Yang, W. (2018). Application of high-speed super-resolution speed microscopy in live primary cilium. Journal of Visualized Experiments, 2018(131). doi: 10.3791/56475.

  • Yang, W. (2022). Nuclear-Cytoplasmic Transport. Array. Springer International Publishing. Retrieved from http://www.worldcat.org/title/nuclear-cytoplasmic-transport/oclc/1022773175?page=citation.

  • Luo, W., Ruba, A., Takao, D., Zweifel, L., Lim, R., Verhey, K., & Yang, W. (2017). Axonemal Lumen Dominates Cytosolic Protein Diffusion inside the Primary Cilium. Scientific Reports, 7(1). doi: 10.1038/s41598-017-16103-z.

  • Mudumbi, K. & Yang, W. (2017). Determination of membrane protein distribution on the nuclear envelope by single-point single-molecule FRAP. Current Protocols in Cell Biology, 2017, 21.11.1-21.11.13. doi: 10.1002/cpcb.27.

  • Ma, J., Kelich, J., Junod, S., & Yang, W. (2017). Super-resolution mapping of scaffold nucleoporins in the nuclear pore complex. Journal of Cell Science, 130(7), 1299-1306. doi: 10.1242/jcs.193912.